ABSTRACT

The field of tissue engineering can be described as the application of biological, chemical, and engineering principles toward the repair, restoration, or regeneration of living tissues using materials, cells, and factors alone or in combination. The definition of regenerative engineering has undergone slight modifications over time but has stayed true to the notion that it is a Convergence field. This chapter discusses aspects of the use of regenerative engineering technologies, techniques, and approaches for the regeneration of bone and soft tissue. Regenerative Engineering can be viewed as a true Convergence field where the coming together of insights and approaches from originally distinct fields fuels the work done in Regenerative Engineering. This new field "Regenerative Engineering" is the convergence of advanced materials science, stem cell science, physics, developmental biology, and clinical translation to answer the grand challenge, i.e., to regenerate complex multicellular organs.