ABSTRACT
The attempt to achieve direct electron transfer between the active site of an enzyme and an electrode is an active area of research [1–6] and is of relevance to the development of an amperometric enzyme electrode. Direct electron transfer between the FADH2 redox centers of glucose oxidase, GOD, and electrode has been achieved via fast redox couple [1–5]. These redox couples can be either covalently or coordinately bound to GOD [1–3], chemically bound to a flexible polymer backbone or a polycationic redox polymer [4–5]. In addition, direct electron transfer between GOD and polypyrrole, PP, has recently been claimed [6]. Electronically conductive polymers, such as PP [7–12] and poly-N-methylpyrrole [12,13] have been proposed as entrapment media for GOD.
