ABSTRACT
Thyroid hormones have multiple effects on cardiac tissue, vasculature, and lipid metabolism. Thyroid disorders are common, especially in older persons, both as overt hyperthyroidism and hypothyroidism and as their subclinical forms. Consequent alterations in thyroid hormone production can have significant effects on cardiac and vascular function and are associated with increased risk of cardiovascular disorders, morbidity, and mortality. Recognition and effective management of altered thyroid function has the potential to correct the adverse effects of thyroid disease on the cardiovascular system and on altered lipid metabolism. Amiodarone, a drug commonly used in the management of cardiac arrhythmias, is associated with a high prevalence of alterations in thyroid function and with development of both hyperthyroidism and hypothyroidism. Careful monitoring of thyroid function will allow prompt recognition and effective management of these disorders.
