This chapter, written for undergraduate medical students and post-graduate doctors in training, presents information on how to manage cough — a case which they are likely to encounter in the future in a general practice setting. It presents the case of a Gemma, aged 2 years, who had a cough for about a week. The cough is slightly rattly, not wheezy, and tends to keep her awake, which makes her more irritable than usual and she is not her usual bouncy self. The chapter provides details of the patients' medical history and the key findings of clinical examination, together with initial investigation results data for evaluation, and helps them develop their skills of clinical reasoning. Key questions then prompt the student to evaluate the patient, and reach a decision regarding their condition and the possible treatment plan.