ABSTRACT

Living organisms are an example of systems that can self-replicate and evolve. In order to understand the assembly of these systems, we need to be able to create artificial systems with similar capabilities. Solution-based systems for deoxyribose nucleic acids (DNA) computation have demonstrated the enormous potential of DNA nanosystems to do computation at the molecular scale. This chapter provides an overview the progress in the field of DNA nanoscience towards the construction of localized hybridization networks and shows the advantages of these networks over non-localized DNA reactions. It focuses on the property and behavior of DNA hybridization reactions on two-dimensional surfaces. Ribose nucleic acids, DNA, peptides, proteins, and enzymes are the foundation of biological diversity. Beyond the conventional properties of DNA, scientists have been using DNA for constructing nanoscale structures, smart materials, and circuits. In order to create a nanoscale breadboard for the construction of localization networks, it is important to understand the process of forming structural artificial DNA nanostructures.