ABSTRACT
Transvaginal or transrectal ultrasound should be used for assessing myometrial and cervical involvement in women with endometrial cancer. The main feature is the presence of disruption of the endometrial-myometrial interphase and the impression of how deep the tumor invades the myometrium. Cervical involvement of endometrial cancer should be suspected when the tumor invades the cervix, disrupting the cervical canal. The diagnostic performance of ultrasound for detecting cervical involvement is similar to that for detecting deep myometrial infiltration. Cervical involvement of endometrial cancer should be suspected when the tumor invades the cervix, disrupting the cervical canal. Tumor histology and tumor grade can be determined reliably in the preoperative endometrial biopsy. The main factors associated with lymph node metastasis are tumor histology, tumor grade, myometrial infiltration depth, cervical involvement, and lymphovascular space involvement. Women at high risk for lymph node involvement are those with tumors with nonendometrioid histology and poorly differentiated endometrioid cancers.
