ABSTRACT

The globalisation of research has resulted in increased location of research in developing countries. Countries in Africa, and developing countries like India, have seen research grow significantly. With emerging infectious diseases such as Ebola and Zika raising the spectre of public health crises throughout the world, an increase in clinical and other kinds of research in developing countries, often the sites of these diseases, becomes inevitable. While the interest in health research involving humans and in its governance in developing countries has increased over the years, with many recent publications considering ethics review systems in developing countries, the emergent policies and the structures they create need more investigation. Research undertaken in the past in many African countries into diseases such as malaria, yellow fever, and trypanosomiasis has contributed immensely to knowledge about the prevention and treatment of these diseases. Clinical trials conducted in developing countries have contributed to public health knowledge and practice in both developing and developed countries.