chapter  8
18 Pages

The Role of Gut Microbiota in the Pathogenesis and Treatment of Obesity

WithStephen J. Walker, Puja B. Patel

Obesity is a condition, influenced by a number of factors, that results in an excessive accumulation of adipose tissue [1]. It has become more prevalent both in developing and industrialized countries, currently thought to impact more than 500 million people worldwide [2]. Obesity occurs when caloric intake exceeds expenditure, resulting in a net gain in body fat [2,3]. It can emerge from interactions among genes and environmental elements, such as diet, food components, and/or lifestyle [2]. Obesity is associated with the onset of a number of other diseases, including cancer, diabetes, nonalcoholic fatty liver disease, cardiovascular disease, and some immune-related disorders [2].