ABSTRACT
Acne vulgaris is a chronic inflammatory disorder of the pilosebaceous unit predominantly affecting the adolescent population (about 85% of subjects aged 12–25 years), although it is not uncommon to have a first outbreak during adulthood in females.1 Its pathogenesis is multifactorial, being related to increased sebum production, keratinocyte hyperproliferation, inflammation, and altered bacterial colonization, primarily by Propionibacterium acnes.1 The primary lesion (from which all others develop) is the microcomedo, which consists of a distention of the follicle filled with sebum and improperly desquamated keratinocytes from the follicular epithelium.1
