ABSTRACT
Preserved cognitive functioning is a prerequisite of the diagnosis of Locked-In Syndrome (LIS). Although it is true that such patients do not have severe intellectual difficulties, some minor problems are common. Patients may tire easily with eye movements and there may be additional visual or hearing problems. The number of cognitive domains affected ranged from one to six; thus all seven patients were shown to have deficits in at least one cognitive domain. The presence of cognitive deficits in patients with LIS was confirmed by Rousseaux et al. 2009. They gave 19 tests to nine LIS patients and two groups of control participants; seven with frontal or fronto-temporal lesions and 16 neurologically intact people. Significant differences were found between the LIS patients and the healthy controls on auditory recognition, oral comprehension of complex sentences, delayed visuo-spatial memory, mental calculation and problem solving. A LIS patient with unilateral spatial neglect has also been reported by Trojano et al.
