ABSTRACT
Bacteria, being microorganisms, are sensitive to various environmental conditions, including chemical pesticides. Chemical pesticides inhibit the bacterial metabolism and also affect the various cellular component of bacteria. Formation of zone of bacterial inhibition around the paper disc indicate the sensitivity of the test chemical to the bacterium. Resistance to particular antibiotic poses serious threat in the management of bacterial population with the same antibiotic or with other antibiotics if the bacteria develop cross resistance to these. Therefore, curing of bacteria for antibiotic resistance is very important for their management. A quinolone resistant mutant when grown on Nabomycin antibiotic reverts back to its natural culture which is then susceptible to quinolone antibiotic, thus curing it of antibiotic resistance. The antibiotic resistant mutant, if inhibited or killed by the same antibiotic, means the plasmid borne antibiotic resistance is cured.
