ABSTRACT
This chapter explores gene modification technologies, the challenges they pose, as well as the ethical and policy ramifications for healthcare delivery and Precision Medicine in particular. Gene editing methods have a wide scope of applications in molecular biology due to their simplicity and precision. The technology may be classified according to many metrics or based on their specific utility. There are reproductive and nonreproductive applications of gene editing. Other classifications are therapeutic and nontherapeutic applications of gene modifications. Gene editing could also be carried out on cluster of genes for desirable clinical significance such as sickle cell anemia (SCA) or enhancing a particular gene function for the "new gene" to become an inheritable material. Other terms are gene corrections, gene modifications, gene additions/deletion, and gene manipulations or genomic bioengineering. The chapter explores the pros and cons of gene modification through the aperture of ethics in order to identify some potential common grounds.
