ABSTRACT
Symptomatic vitreous floaters are common over the age of 30 years but are mostly ignored by the individual. Some have considerable debris in the vitreous either from pathology or from general degeneration. Patients with multifocal lens implants may find vitreous opacities more problematic. The most frequent severe developmental anomaly in the vitreous is persistent hyperplastic primary vitreous. Retinal angioma can occur as a solitary lesion not associated with systemic disease or as multiple lesions in von Hipple–Lindau disease (VHL). Idiopathic cases present later, with mean age at presentation of 36 years, than in VHL. Marfan's syndrome is a connective tissue disorder which affects the skeleton, lungs, eyes, heart and blood vessels. Patients with subarachnoid haemorrhage from intracranial aneurysms may develop vitreous bleeds. Histopathology has shown haemorrhage in the vitreous, subhyloid, sub-internal limiting membrane (ILM), intraretinal and in the optic nerve and the optic nerve sheath. Retinal electrodes are being designed and trailed in patients with retinitis pigmentosa.
