ABSTRACT
Hybrid feedback and feed-forward control structures are common in biological systems. This chapter explains a hybrid time- data- driven control framework for micro-/nanoscale devices or systems with hybrid sensing signals. This is significant for developing a control theory for manipulation of cellular systems and for controlling micro-/nanoscale engineered systems. The chapter aims to make several original contributions in controlling micro-/nanoscale systems. It focuses on the procedure of constructing the corresponding time-driven and data-driven planners to generate the required reference trajectory. The chapter utilizes a switching control mechanism to switch planners. In principle, each channel can accommodate signals in different formats, including no signal, continuous-time signal, and hybrid signal in cases where that signal is either continuous or discrete. For cellular control, accessible measurement is not always persistent, but often exhibits a hybrid characteristic. In addition, to control biological cellular systems requiring rapid response in nanoscale, a feedback control is not guaranteed to be effective due to relatively slow measurements.
