ABSTRACT
A biosensor is an analytical device that determines the specific interactions between biological molecules. The electrochemical quartz crystal microbalance (EQCM) system is a very convenient and powerful tool for creating electropolymerized thin films on the electrode surface of the quartz crystal the working electrode using cyclic voltammetry (CV). Biosensors are commonly used in various fields such as food industry, environmental field, medicine, and drug discovery regarding its advantages such as label-free detection of molecules, fast response time, minimum sample pretreatment, and high sample throughput. The quartz crystal microbalance (QCM) as a Piezoelectric (PZ) sensor is fundamentally a mass sensing device with the ability to measure very small amounts of mass changes on a quartz crystal resonator (QCR) in real time. Enzyme biosensors based on highly specific enzymatic reactions have been widely exploited (in clinical and food analysis). In general, the QCM enzyme biosensors are used for the measurement of mass deposition of the product molecule from the enzymatic reaction.
