ABSTRACT
Drug targeting is a promising strategy for efficient treatment of various serious diseases such as cancer. The primary goal of this concept is to provide precise delivery of therapeutic agents into pathological area, while 384avoiding negative impact onto healthy tissues. Through this approach, high therapeutic efficacy of the drug can be attained while experiencing minimum side effects. Recently, nano-sized carriers have received great attention as delivery systems which can load, bring, and release the drugs in a localized area. Accurate drug delivery can be achieved either via passive targeting, which is-based on enhanced vascular permeability in affected zone, or active targeting, which can be achieved by decoration of nanocarriers surface with ligands that have high affinity toward the targeted area. In this chapter, general methods and means of drug targeting-based on nanomedicine have been discussed.
