ABSTRACT
Capillary electrophoresis is a technique of high speed, good sensitivity, low limit of detection, and quantification with economic experimental price. Thermooptical absorbance is a laser-based detection device used in capillary electrophoresis. In this detection method, a beam of high-energy laser is focused onto the separation capillary and the analytes are excited. Data integration is the final and imperative part of capillary electrophoresis equipment, which provides direct information about the analyses. good hyphenation of capillary electrophoresis equipment with atomic absorption spectrometry (AAS), inductively coupled plasma (ICP) and mass devices should be developed, which may result into superior reproducibility and small limits of detection. AAS is being used as a potent instrument in the quantitative analysis of trace elements. AAS has been hyphenated at several occasions with capillary electrophoresis, especially in the application of metal ion analysis and compounds having metal ions such as hemoglobin and cyanocobalamine.
