ABSTRACT

Chiral recognition has been among the most attractive fields of research, particularly to the chromatography family due to a large number of concerns in the fields, which include life science, food science, drug discovery, and environmental science. As it is well acknowledged that a deeper understanding of biological processes requires a multidisciplinary approach employing the tools of biology, chemistry, and physics. Such understanding involves study of bioactive molecules and their functions, which include quantification and purification. Exploring many structural alternatives and their corresponding spectroscopic and thermodynamic properties is an important step in cross-validating theory and experiment, forming the basis for further elaboration toward more realistic models. The molecular modeling techniques based on the docking and absorption further enable to elucidate the chiral recognition mechanisms, which can only be imagined based on the outcome of the capillary electrophoresis (CE) separation results.