ABSTRACT

Expanding on the highly successful first edition, this second edition of Proton Therapy Physics has been completely restructured and updated throughout, and includes several new chapters. Suitable for both newcomers in medical physics and more seasoned specialists in radiation oncology, this book provides an in-depth overview of the physics of this radiation therapy modality, eliminating the need to dig through information scattered across medical physics literature.

After tracing the history of proton therapy, the book explores the atomic and nuclear physics background necessary for understanding proton interactions with tissue. The text then covers dosimetry, including beam delivery, shielding aspects, computer simulations, detector systems and measuring techniques for reference dosimetry. Important for daily operations, acceptance testing, commissioning, quality assurance and monitor unit calibrations are outlined. The book moves on to discussions of treatment planning for single- and multiple-field uniform doses, dose calculation concepts and algorithms, and precision and uncertainties for nonmoving and moving targets. Imaging for treatment guidance as well as treatment monitoring is outlined. Finally, the biological implications of using protons from a physics perspective are discussed.

This book is an ideal practical guide for physicians, dosimetrists, radiation therapists, and physicists who already have some experience in radiation oncology. It is also an invaluable reference for graduate students in medical physics programs, physicians in their last year of medical school or residency, and those considering a career in medical physics.

Features:

  • Updated with the latest technologies and methods in the field, covering all delivery methods of proton therapy, including beam scanning and passive scattering
  • Discusses clinical aspects, such as treatment planning and quality assurance
  • Offers insight on the past, present, and future of proton therapy from a physics perspective

chapter |6 pages

Introduction

part 1|60 pages

Background

chapter 1|18 pages

Proton Therapy

History and Rationale

part 2|2 pages

Beam Delivery

part 4|74 pages

Operation

part 6|66 pages

Imaging

chapter 20|27 pages

Proton Image Guidance *

chapter 21|35 pages

In Vivo Treatment Verification *

part 7|60 pages

Biological Effects

chapter 22|34 pages

The Physics of Proton Biology *

chapter 23|24 pages

Fully Exploiting the Benefits of Protons *

Using Risk Models for Normal Tissue Complications in Treatment Optimization