ABSTRACT

This chapter shows that examples of how to analyze dose-response data that are continuous. It is a common type of dose-response data obtained in biology, toxicology, and many other fields. Specifically, a continuous response is a quantitative measurement that may take any value within a certain range and is usually expressed in a quantitative unit such as colour, length, mass, and volume. There may also be other reasons for the absence or presence of a lower limit such as a systematic measurement error that prevents observation of response values asymptotically approaching 0. The variables conc and weight contain the concentration and corresponding weight measurements. The reduced variation observed for the larger concentrations mostly determining the lower limit was weighed up, reflecting the assumption of variance homogeneity. Hormesis is a stimulatory response to low levels of stress, such as low concentrations of organic or inorganic chemicals or radiation.