(L,,,U,,), where L — df,
A pharmaceutical company is interested in conducting an experiment to recommend in-house dissolution specifications for the tablets of a pharmaceutical compound. Three batches of granulation were each made into three tablet
strengths (200 mg, 300 mg, and 400 mg). Twelve dissolution assays were performed at 2, 4, 8, and 14 h on each of the nine batches by strength combinations. The results are given in Table 5.5.2. The means and standard deviations for each batch-by-strength combination are given in Tables 5.5.3 and 5.5.4.