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The ANOVA table with expected mean squares for the two-way crossed-classification mixed model with interaction is given in Table 3.5.5. Table 3.5.6 summarizes ANOVA estimators and (1 — a) X 100% confidence intervals for

and QA. Searle et al. (1992) also gave the MLE for the variance components under various conditions for model (3.5.24). Example 3.5.2

A recovery study was conducted to evaluate an assay method at two different laboratories. At each laboratory three levels of potency were added: 80%, 100%, and 120% of label claim. There were three replicates at each level of potency at each laboratory. The actual recovered amounts in terms of label claim and the percent recovery are given in Table 3.5.7.