ABSTRACT

Biopolymers of marine products are involved in terms of drug development, which led to extensive preclinical studies, clinical trials in several therapeutic areas, including cancer, and for several biomedical applications. Biomaterials are the materials intended to interface with biological systems to evaluate, treat, augment, or replace any tissue, organ, or function of the body. Calcium alginate is reputed to be a hemostatic agent that stimulates the clotting of blood in situ, which is subsequently absorbed in the tissue. The significance of in vitro cell culture studies are of great consideration, in time-efficient treatment of cancer patients, and an understanding of developmental biology and mechanisms of stem cell differentiation. Regeneration of functional tissues and incorporation of new tissues require adhesion, migration, proliferation, and organization of new and old cells at the injured site. Nanoporous alginate gels have been investigated for the delivery of a variety of low-molecular-weight drugs leading to rapid diffusion of small molecules through the gel.