ABSTRACT

Pharmaceutical drug targeting is considered as the approach of delivering the drugs molecules to specific receptors, targeting tissues or any other specific parts of the body to one need to target the drug molecule exclusively. Magnetic drug delivery by particulate carriers is a very efficient method of delivering a drug to localized disease site. In case of tumor targeting, microsphere can internalize by tumor cells due to its much increased phagocytic activity as compared to normal cells. The use of magnetic force for the site-specific delivery by using albumin microspheres containing magnetic appears be a promising strategy. The magnetically carried microspheres and liposomes were employed to selectively transport the curare like drugs to the muscles of one of the limbs of the cat. The magnetic microspheres are separated from non-magnetic ones by exposing the mixture to magnetic field and collecting the particles retained near the magnet. Magnetic technology is widely used for external programming of cardiac pacemakers.