ABSTRACT

This chapter discusses applications of the chemical exchange satu-

ration transfer (CEST) technique in the context of hyperpolarized

(hp) exchanging xenon. For basic aspects of CEST with 1H magnetic

resonance imaging (MRI), the reader is referred to the previous

chapters of this book. Herein we focus on systems with hp xenon

that does not participate in covalent bonds (like in diaCEST) or

ligand coordination (paraCEST). Instead, it is a somewhat special

case of compartmental exchange as described in the proposed

nomenclature by van Zijl et al. [1].