ABSTRACT
Dissolution testing of conventional and non-conventional dosage
forms was introduced in the 1960s. Dissolution testing is a
compendial test that is used by all pharmacopeias to evaluate drug
release. Apart from the standardized tests, there are several non-
compendial methods which are qualified and validated for use in
drug release testing. This chapter is divided into five sections. The
first section provides an introduction stating the importance of
dissolution testing. The second section briefly discusses existing
compendial methods along with any non-compendial modifications.
The third section describes non-compendial apparatus for different
types of dosage forms. The fourth section explains the various
detection techniques such as UV imaging with Raman spectroscopy,
FTIR-ATR, and fiber optics. The final section provides a summary of
all findings.