ABSTRACT
The use of microparticles of degradable polyhydroxyalkanoates to repair model skin defects was reported by researchers of the Siberian Federal University in a study conducted within the framework of mega project “Biotechnology of Novel Biomaterials”. Reconstructive medicine needs novel materials for effective regeneration of skin injured due to burns, traumas, and surgical interventions. Principles and methods of replacing the integrity of the skin are determined by such factors as the depth and severity of the injury, the phase of the wound healing process, the wound location, the degree of microbial invasion, patient’s other diseases, and the drugs taken by the patient. The basic principle of wound therapy is wound debridement and creation of the optimal conditions for wound healing. The quality of skin grafts is certainly influenced by the method and conditions of storage. Transdermal skin treatment requires the absorption of drug through the skin into the body.
