ABSTRACT
Abstract ................................................................................................. 124 10.1 Introduction ................................................................................ 124 10.2 The Importance of Electrospun Nanofibers in
Tissue Engineering Scaffolds ..................................................... 126 10.2.1 Electrospinning of Nanofibers Mats ............................ 130 10.2.2 Microscopic Model ...................................................... 132 10.2.3 The Importance of Dimensionless Analysis ................. 132 10.2.4 Governing Relations in Bead-Spring Model ................ 134 10.2.5 Simulation of Bead-Spring Model ............................... 135 10.3 Conclusion ................................................................................. 136 Keywords .............................................................................................. 137 References ............................................................................................. 138
ABSTRACT
Electrospinning has emerged recently as a very widespread technology to produce synthetic nanofibrous structures and best candidates for many important applications like scaffolds in tissue engineering. Nanofibrous scaffolds are intended to provide improved environments for cell attachment, migration, proliferation, and differentiation when compared with traditional scaffolds. Producing and creating porosity is the primary challenge of tissue engineering scaffolds. Also, the most significant challenge in this process is to attain uniform nanofibers consistently. For these causes, controlling, producing of electrospun nanofiber becomes important. However, Analysis dynamics of jet formation and its instability is difficult during the process. This instability made unsuitable aligned nanofibers, which are vital for producing scaffolds. For making more suitable and applicative scaffolds, we should control this instability. More suitable and simplest and fastest way for controlling instability is using modeling and computer simulations. The main aim of this article is simulating behavior of the electrospinning process using bead-spring model for better observation.
