ABSTRACT
Sensors and agents that would allow accurate, fast detection of hydrogen sulfide have long been desired by physicians and other workers in this field. A method that would allow real-time, or near-real-time, determination of H2S intoxication could have many applications, for example
• Aid in emergency room diagnosing • Establish cause of death • Warn of chronic low-level H2S exposure
The most commonly studied biomarkers are
• Sulfide in blood • Thiosulfate in blood • Thiosulfate in urine
Thiosulfate is a major metabolite of hydrogen sulfide. In healthy nonexposed people, thiosulfate occurs in very low concentrations in both the blood and urine. Finding it can be taken as a strong indication of H2S poisoning.
