chapter  4
18 Pages

Mechanical Properties of Polymeric Films Prepared from Aqueous Dispersions

Pharmaceutically acceptable polymers used in the lm coating of solid dosage forms are primarily based on acrylic or cellulosic polymers. Many of these polymers for controlled release applications have been formulated into aqueous colloidal dispersions (e.g., latices or pseudolatices) in order to overcome the high costs, potential toxicities, and environmental concerns associated with the use of organic polymer solutions [1-3]. Film coating has been successfully utilized to control the release of active ingredients, prevent interaction between ingredients, increase the strength of the dosage form to maintain product integrity during shipping, and protect the drug from the environment [3-8].