chapter  9
40 Pages

Chemistry and Application Properties of Poly(meth)acrylate Systems

Introduction ....................................................................................................................................208 History of Poly(meth)acrylates and Their Applications ............................................................208 Denitions of Latices and Their Physicochemical Specications ............................................209 Systematics of Nomenclature and Commercial Products .........................................................209 Other Pharmaceutical Applications Besides Coating ................................................................ 210

Chemistry, Production, and Quality ............................................................................................... 210 Chemical Structure .................................................................................................................... 210

Soluble Polymers .................................................................................................................. 211 Insoluble Polymers ............................................................................................................... 214

Manufacture .............................................................................................................................. 215 Bulk and Solution Polymerization ....................................................................................... 215 Emulsion Polymerization ..................................................................................................... 215 Further Processing ................................................................................................................ 216

Pharmaceutical Quality ............................................................................................................. 217 Polymer Characterization and Quality Control .................................................................... 217 Toxicology and Registration ................................................................................................. 218

Properties, Handling, and Functions .............................................................................................. 219 Film-Forming Mechanisms ....................................................................................................... 219 Compatibility and Formulations ...............................................................................................220