ABSTRACT
The eye is a complex organ of the human body with distinguished anatomy and physiology. The optical system is designed with different segments termed the protective segment, anterior segment, posterior segment, and a visual system pathway. The protective segment is composed of the orbit, lids, and sclera. The anterior pole of the eye comprises the cornea, aqueous humor, iris, and ciliary body, whereas the posterior pole is composed of the retina and vitreous humor (Sandeep et al. 2013; Figure 8.1). The visual system pathway constitutes the optic nerve, optic tracts, and visual cortex. The anterior segment of the eye is affected by diseases such as dry eye, allergic conjunctivitis, glaucoma (Rathore and Nema 2009; Thakur and Kashiv 2011,
8.3.3.8 Afnity of RGD Motif with Integrin Receptor after Coupling to Activated Polymer .......................................... 193
8.3.3.9 Conjugation of RGD Peptide with Copolymer (Surface Functionalization) ................................................ 193
8.3.4 Glaucoma .......................................................................................... 194 8.3.4.1 Pathogenesis of Glaucoma ................................................. 194 8.3.4.2 Current Treatment Options Adopted for Glaucoma .......... 195 8.3.4.3 Drug Targets for Novel Drug Delivery Systems
to Treat Glaucoma .............................................................. 195 8.4 Novel Ocular Drug Delivery Systems .......................................................... 195
8.4.1 Nanoparticulate-Based Ocular Drug Delivery Systems ................... 197 8.4.2 Liposomal-Based Ocular Drug Delivery Systems ........................... 199 8.4.3 Nanodispersion/Nanocrystals-Based Ocular Drug Delivery
Systems ............................................................................................. 199 8.4.4 Emulsions-Based Ocular Drug Delivery Systems ............................200
