ABSTRACT
The main motivation to develop and improve the computation of particle-particle or particle-droplet interaction during collision in a dryer wide simulation of the spray-drying process is to predict agglomeration and wall deposition. The prediction of agglomeration within the spray-drying chamber is important because, in the actual process, this affects the bulk density of the spray-dried powder. The bulk density of the spray-dried powder will significantly affect the flowability and the packaging of the product, although this is further manipulated at the second or third stage of drying. Apart from that, agglomerates with different size and mass will traverse across the drying chamber different owing to the different inertia and drag. Another importance of agglomeration within the drying chamber is that it provides an avenue in the elimination of fine particles. These particles are typically separated in the cyclone and returned to the chamber for size enlargement. In view of this, what is actually the current state-of-the-art of agglomeration prediction in spray dryers?
