chapter  8
12 Pages

Antihypertension Effects of Green Coffee Bean Extract and Chlorogenic Acids

Coffee is one of the most widely consumed beverages in the world; therefore, even potentially small health benets associated with coffee intake may have important implications for public health.

In a recent National Institutes of Health-AARP Diet and Health Study, 229,119 men and 173,141 women were monitored from 1995 to 2008 to examine the association of coffee drinking with subsequent total and cause-specic mortality [1]. Participants were 50-71 years of age at baseline. During 5,148,760 person-year of follow-up from 1995 to 2008, a total of 33,731 men and 18,784 women died. In ageadjusted models, the risk of death was increased among coffee drinkers. However, coffee drinkers were also more likely to smoke, and after adjustment for smoking status and other potential confounders, there was a signicant inverse association between coffee consumption and mortality. Inverse associations were observed for deaths due to heart disease, respiratory disease, stroke, injuries and accidents, diabetes, and infections, but not for cancer-related deaths.