ABSTRACT
The outcome of poisoning treatment depends on numerous factors, such as the type of substance involved, the degree of exposure, the previous health of the individual exposed, and the time between exposure and initiation of treatment. The treatment of poisoning might begin with asymptomatic individuals with known or likely toxic exposures, or later when toxicity is more evident and life-threatening. Information from any source that relates to a poisoning situation is collected. Specifically, information is sought on the identity of the toxicant, the amount involved, and approximately when the exposure occurred. Toxidromes are a constellation of signs and symptoms suggestive of a particular class of toxicants. They can narrow the range of diagnostic possibilities, suggest management approaches, and provide guidance for targeting additional clinical and laboratory testing. Treatment of acute poisoning is based on the symptomatic management of life-threatening symptoms such as seizures, cardiovascular collapse, hyperthermia, and electrolyte imbalances.
