ABSTRACT
In this chapter, the design of graphene-and biomolecule-based nanosensors and nanodevices is surveyed with emphasis on using graphene-based eld-effect-transistor (GFET)-like structures as sensing substrates and DNA aptamers as sensing elements. In the context of designing nanobiosensors, the elements of sensing, Raman spectroscopy techniques and their application in this process, and functionalization of graphene using peptides are delineated. To understand such devices, background materials are discussed and a combination of theoretical considerations and empirical observations are reviewed on a case-by-case basis.
