ABSTRACT

This book addresses the five core components of an investment appraisal; strategic, economic, commercial, financial and project management. It provides managers and policy makers in healthcare, government and private sector organisations with a tried and tested decision making tool and supporting guidance to improve capital investment decisions. It is a practical guide that includes numerous examples from the health service as well as lessons learnt from other public sector areas where best practice has been demonstrated. Comprehensively illustrated with case studies, checklists and templates to aid decision making, it offers practical, evidence-based guidance, clear summaries and pointers to accessing further information.

chapter 1|3 pages

Introduction

chapter 2|4 pages

Pharmacology overview

chapter 3|6 pages

Pharmacokinetics

chapter 4|6 pages

Pharmacodynamics

chapter 5|3 pages

Clinical trials

chapter 6|5 pages

Receptors

chapter 7|3 pages

The autonomic system I: introduction

chapter 10|9 pages

The neuromuscular junction (NMJ)

chapter 11|4 pages

Myasthenia

chapter 12|7 pages

5-hydroxytryptamine (5-HT; serotonin)

chapter 13|3 pages

Eiconasoids

part 15|2 pages

Systems targeted by drugs

chapter 16|7 pages

Diuretics

chapter 17|7 pages

Drugs and the heart I: heart failure

chapter 20|5 pages

Drugs and the heart IV: angina pectoris

chapter 21|7 pages

Drugs and the heart V: antiplatelet drugs

chapter 23|6 pages

Anticoagulants II: oral anticoagulants

chapter 24|6 pages

Fibrinolytic and antifi brinolytic drugs

chapter 25|3 pages

Hypertension I: introduction

chapter 26|14 pages

Hypertension II: treatment

chapter 27|5 pages

Infl ammation I: introduction

chapter 32|6 pages

Paracetamol (USA: acetaminophen)

chapter 33|6 pages

Opioid analgesics

chapter 34|3 pages

Local anaesthetics

chapter 35|5 pages

General anaesthetics

chapter 36|6 pages

Parkinson’s disease

chapter 37|6 pages

Epilepsy

part 38|2 pages

Alzheimer’s disease

chapter 39|5 pages

Antidepressant drugs

chapter 40|3 pages

Anxiolytic drugs

chapter 41|5 pages

Anti-infective drugs (antibiotics)

chapter 42|6 pages

Chemotherapy for malignancy (cancer)