ABSTRACT

Learning objectives ■ Cancer chemotherapy ■ Mini glossary ■ Classes of drugs currently used for chemotherapy ■ Alkylating agents ■ Antimetabolites ■ Topoisomerase inhibitors ■ Antibiotics ■ Hormones and analogues ■ Breast

cancer ■ Estrogens ■ Progestogens ■ Hormone antagonists and aromatase inhibitors ■ Prostate cancer ■ Monoclonal antibodies

Learning objectives Know the heading names for the classes of drugs given. ■ Be able to give examples of drugs listed in all the categories listed. ■ Know important disadvantages and adverse effects of alkylating agents. ■ Know what is meant by antimetabolites and topoisomerase inhibitors. ■ Be able to give a brief account of hormone analogues and antagonists in ■ the treatment of cancer. Be able to give examples of monoclonal antibodies and their uses to treat ■ cancer.