ABSTRACT

Learning objectives Know the routes of administration of drugs. ■ Know what the choice of route depends on. ■ Be able to list the body compartments given. ■ Be acquainted with the concept of the volume of distribution. ■ Know what the partition coeffi cient is. ■ Be able to give a brief account of the signifi cance of plasma binding of ■ drugs. Be able to give a brief account of the principles of drug metabolism. ■ Know the routes of drug excretion and how excretion is measured. ■

FIGURE 3.1 Pathways of drugs which act systemically.