ABSTRACT
Interactions are more likely to be a problem:
with the following drug groups: antacids, antibiotics, anticoagulants, antidepressants, antidiabetics, anticonvulsants, antifungals, cardiac drugs, corticosteroids, diuretics, NSAIDs and ulcer healing drugs
with the following drugs (in descending order of number of likely interactions): carbamazepine, warfarin, diltiazem, verapamil, furosemide, cimetidine, methotrimeprazine, itraconazole, ketoconazole, amiodarone, dexamethasone, prednisolone and erythromycin
in drugs with a narrow margin between therapeutic and toxic doses, e.g. digoxin
when an interacting drug is started or stopped.