ABSTRACT
Skin
– epidermis + dermis
Epidermis:
– derived from ectoderm
– stratified squamous epithelium
– avascular
– (from outermost to innermost): stratum corneum → stratum lucidum → stratum granulosum → stratum spinosum → stratum basale (contains melanin)
– keratinocytes (synthesise structural proteins)
– Merkel cells
– Langerhans cells (dendritic cells that present antigens to lymphocytes)
– melanocytes
Basement membrane
Dermis:
– derived from mesoderm
– vascular layer
– fibroblasts
– blood vessels
– nerves
– sweat glands
– hair follicles
