ABSTRACT
This chapter describes the progression of discoveries and subsequent advancements in both the diagnosis and treatment of venous and lymphatic diseases. Nicola Massa, an Italian human anatomist, described the renal lymphatic vessels and pondered their function. The lymphatic system was recognized as central to the immune system of the body. Lymphatic reconstruction via microsurgery, lymph node transplant, and excisional surgery have been the mainstays of therapeutic modalities. The enormous costs associated with venous diseases are associated with the management of subsequent venous ulceration and complications. The history of venous disease is rich, fascinating, and far-reaching. Many of the same scientists who made significant contributions to the discovery of varicose veins and chronic venous insufficiency also advanced our understanding of the lymphatic system. Lymphatic reconstruction via microsurgery, lymph node transplant, and excisional surgery have been the mainstays of therapeutic modalities.
