ABSTRACT
Nanotoxicology is the area of toxicology specifically dealing with nano-materials (NMs) or nanoparticles (NPs). Advances in nanoscience and nanoengineering technology have provided both benefits and risks to human safety as nanoparticles are now being used in many consumer products, such as foods, cosmetics, biosensors, energy, household products, electronic devices, and drug delivery systems and their applications continue to increase rapidly (Zhao and Castranova, 2011). In general, a NP is defined as a particle with a diameter between 1 and 100 nm (ISO, 2008; SCENIHR, 2010), which enters cells either via energy-dependent endocytosis, transmembrane channels, or membrane penetration and may produce 488adverse effects. Due to rapid increase in nanotoxicological research, a database, NHECD (Nano Health-Environment Commented Database), was developed and is available at: https://www.nhecd-fp7.eu (CORDIS, 2016).
