ABSTRACT
Neuroscience is a field of increasing relevance for therapists and patients, daunting due to the proliferation of technical material and research. Discussion of the neurobiology of trauma with consideration for male sexual abuse is important for understanding clinical approaches directly modifying brain activity. The Dorsolateral prefrontal cortex (DLPFC) is an important part of the frontal cortex involved with directing attentional and working memory resources and managing awareness of emotional states. The Autonomic nervous system (ANS) regulates basic essential physiologic processes, without the need for conscious control, and innervates the entire body. Research investigating the psychopharmacologic treatment of post-traumatic stress disorder (PTSD) is limited, and developing. Antipsychotics have the clearest indication for use in PTSD with co-occurring psychotic symptoms, in only open-label trials. Studies in humans suggest cannabis may improve PTSD symptoms, including poor sleep, nightmares, and hyper-arousal. There is limited research on medication management for dissociative disorders.
