ABSTRACT
Fluorescein angiography is the most common type of angiography utilized in ophthalmology. Fluorescein dye fills and illuminates the vessels of the retina and choroid as images are captured at the same time. Fluorescein angiography is most commonly performed with a mydriatic fundus camera using still photography. Some non-mydriatic systems and wide-angle systems also offer angiography as a feature. Scanning laser ophthalmoscope systems can perform high-speed video angiography. The basis of a good fluorescein angiogram is good fundus photography technique. In fact, fluorescein angiography can be more forgiving than fundus photography due to a filtration system that removes everything but the fluorescence. In a fluorescein angiogram, the dye binds to blood; specifically, it binds to albumens (proteins) in the blood plasma. In addition to being administered intravenously for a fluorescein angio-gram, fluorescein sodium is also used topically on the eye to visualize corneal epithelium defects, assist in contact lens fitting, and evaluate dry eye.
