ABSTRACT
Patients with what we now term primary progressive aphasia (PPA) were first described over a century ago when Arnold Pick reported cases with predominant language impairment due to unspecific brain atrophy (Pick, 1892, 1904). In his landmark paper, “On the symptomatology of left-sided temporal lobe atrophy”, Pick described three cases, with what corresponds to what was later termed semantic
Address correspondence to: Cristian E. Leyton, Neuroscience Research Australia, Barker Street, Randwick, NSW 2031, Australia. E-mail: c.leyton@neura.edu.au
Aphasiology, 2014 Vol. 28, Nos. 8-9, 909-921, https://dx.doi.org/10.1080/02687038.2013.869306
© 2014 Taylor & Francis
CLINICAL PERSPECTIVES ON PRIMARY PROGRESSIVE APHASIA
dementia, characterised by striking memory loss for names (amnesic aphasia) that culminated in almost complete loss of speech accompanied by changes in personality.
