HIV disease is no longer a death sentence; it has become a chronic illness. Chronic health care systems require a diverse array of both medical and social support services. This is especially true of HIV disease, which often involves physical health care, mental health care, and substance abuse treatment, as well as the provision of basic necessities, such as housing and income, to individuals who are socially marginalized. In order to provide for wholistic care, these diverse systems need to be integrated. Klinkenberg and Sacks (2004) have argued that treatment programs for multiply diagnosed HIV-positive individuals must provide some level of integrated care to be effective. Successful integration of HIV care systems will have important lessons for communities seeking to integrate health care services for other chronic care populations, as well as the elderly.