ABSTRACT

In support of the aforementioned concepts and models, this chapter provides specific examples of parallel design thinking between architectural research and cell biology that has been garnered over six years of research and education within LabStudio and now in its current formations. It highlights specific project work on the topic of cellular networking behavior through examples that examine the nature of nonlinearities, emergent properties, and loosely coupled modules that are cardinal features of complexity. For the networking projects, the chapter investigates part-to-whole relationships during capillary formation by lung endothelial cells. At the biological level, coordinated cellular networking, a component of angiogenesis, is required to form the exquisite fractal network that emerges in the developing and mature lung to facilitate efficient gas exchange from birth onwards. The purpose of the airway-capillary interface is to provide oxygen from the air to red blood cells within the capillaries.