ABSTRACT

The neocortex is the largest part of the mammalian brain, and appears to be the least genetically determined. Much of its structure and connectivity depends on electrical activity during development. Because various neocortical areas are very similar in anatomical structure and exhibit similar developmental phenomena, it has been suggested that a common organizing mechanism underlies their ontogeny [18]. By modeling the development of a well-understood substructure such as the primary visual cortex, it might be possible to elucidate this common mechanism.