ABSTRACT
Since forwards propagation takes place via cell membranes and synapses in this model, using widely known mechanisms, no further explanation is required for the medium of signal propagation. Backwards error signals, however, are propagated inside the cell via cytoskeleton, which is a novelty of our proposed model, and thus requires explanation for both signal initiation and signal propagation. We suggest ~andidate biophysical mechanisms for signal initiation at MT ends or actin and neurofilaments and for signal propagation along protein polymer strands.
